"[Tim] Keller was addressing the cultural objections people have to the Bible, e.g. sexual mores, marriage, patriarchy, etc. He pointed out that what his audience in NYC would consider oppressive sexual ethics would be considered liberal in the Middle East. He asked them to consider what culture 100 years ago would not have objected to in the Bible that they object to, and what they don't object to now that may be considered ignorant and backward by their great grandchildren.
"He said if the Bible is from God and not from culture, wouldn't we expect that it would conflict with every culture at every time? And that is what we see. If it was produced merely by men living in a particular culture, it would reflect a particular culture rather than conflict with it. So rather than cultural objections working against the Bible, it's actually an indication that it stands outside of culture And that's a line of argument that the Bible is from God, not man."